Rather than simply splitting pages horizontally or vertically, you can tile pages into smaller section both horizontally and vertically at the same time. (Handy, for instance, when you want to print a large graphic onto several pieces of paper to later assemble by hand into a large poster.)
The tiling feature defaults to tiling pages in four, but you can specify a grid of any number of rows and columns, including an optional overlap (red zones in screenshot above).